Photo: Sam Dunne (4481 views)
Syphilis can cause massive destruction to the nose, giving rise to the formation of "No Nose Clubs" in the 18th Century. This painted silver nose mounted on a spectacle frame was worn by a women who had suffered this fate. Apparently, she later sold the nose to her doctor for 3 pounds citing that she had remarried and that her husband preferred her without it.
Superhuman at Wellcome Collection